Vaginal & Uterine Microbiome

Female Fertility

Vaginal & Uterine Microbiome

The reproductive microbiome — vaginal, uterine and gut — is emerging as one of the most significant and underappreciated influences on female fertility and implantation success.

Why It Matters

The Microbiome & Reproductive Success

Groundbreaking research in reproductive medicine has revealed that the vaginal and uterine microbiome are not sterile environments — they are active ecosystems that profoundly influence sperm survival, embryo development and successful implantation.

At Levitas, we incorporate microbiome testing as part of our comprehensive female fertility assessment, particularly for those experiencing recurrent implantation failure, unexplained infertility, or recurrent miscarriage.

Vaginal Microbiome

The vaginal microbiome is predominantly Lactobacillus-dominant in a healthy reproductive environment. Disruptions — through infections, dysbiosis or imbalanced pH — can impair sperm survival, increase inflammation and reduce implantation success.

  • Lactobacillus dominance and fertility
  • Bacterial vaginosis and implantation failure
  • Microbiome-informed treatment protocols
  • Restoration of healthy vaginal flora

Uterine Microbiome

The uterine cavity has its own distinct microbiome that influences embryo implantation. An abnormal endometrial microbiome — even without obvious symptoms — is associated with recurrent implantation failure and early pregnancy loss.

  • Endometrial microbiome assessment
  • Impact on implantation and IVF outcomes
  • Chronic endometritis screening
  • Targeted probiotic and antimicrobial treatment

Gut-Reproductive Axis

The gut microbiome communicates bidirectionally with the reproductive system. Poor gut health drives systemic inflammation, disrupts oestrogen metabolism via the oestrobolome, and can negatively impact the vaginal and uterine microbiome.

  • Gut microbiome testing (Microba)
  • Oestrogen recycling and the oestrobolome
  • Systemic inflammation reduction
  • Targeted gut restoration protocols

Food Allergies & Sensitivities

Unrecognised food allergies and sensitivities can fuel systemic and localised inflammation that compromises reproductive function. Identifying and eliminating triggers is a key step in reducing inflammatory burden.

  • IgG and IgE food sensitivity testing
  • Elimination and reintroduction protocols
  • Gut permeability ("leaky gut") assessment
  • Anti-inflammatory nutrition strategies

Our Approach

Personalised Microbiome Optimisation

Microbiome health is best understood in context. At Levitas, we integrate microbiome testing with your full hormonal, immune and nutritional profile to design a targeted restoration protocol. Treatment may include targeted probiotics, dietary modification, antimicrobial protocols and gut restoration strategies.

This is an area where cutting-edge research is rapidly translating into clinical practice, and we are committed to offering our patients access to the latest evidence-based interventions.

Explore Microbiome Testing

Our clinical team can assess your reproductive microbiome as part of a comprehensive fertility optimisation pathway.